Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu, Rt, Pm
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Description
The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.
Bioinformatics
| Entrez |
Human
Rat
|
| Uniprot |
Human
Human
Human
Rat
|
| Product By Gene ID |
1816 |
| Alternate Names |
- D(1B) dopamine receptor
- D(5) dopamine receptor
- D1beta dopamine receptor
- Dopamine D5 receptor
- dopamine receptor D1B
- dopamine receptor D5
- DRD1BDBDR
- DRD1L2MGC10601
|
