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Dopamine D1R/DRD1 Antibody (SG2-D1a) [DyLight 680]

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Product Details

Summary
Reactivity Mu, Rt, Bv(-), Ca(-), Hu(-), Po(-), Rb(-), Sh(-)Species Glossary
Applications WB, ICC/IF, IHC, IHC
Clone
SG2-D1a
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-60017AF350
Alexa Fluor 405
NB110-60017AF405
Alexa Fluor 488
NB110-60017AF488
Alexa Fluor 532
NB110-60017AF532
Alexa Fluor 594
NB110-60017AF594
Alexa Fluor 647
NB110-60017AF647
Alexa Fluor 700
NB110-60017AF700
Alexa Fluor 750
NB110-60017AF750
Biotin
NB110-60017B
CoraFluor 1
NB110-60017CL1
DyLight 350
NB110-60017UV
DyLight 405
NB110-60017V
DyLight 488
NB110-60017G
DyLight 550
NB110-60017R
DyLight 594
NB110-60017DL594
DyLight 650
NB110-60017C
DyLight 755
NB110-60017IR
FITC
NB110-60017F
HRP
NB110-60017H
Janelia Fluor 525
NB110-60017JF525
Janelia Fluor 549
NB110-60017JF549
Janelia Fluor 585
NB110-60017JF585
Janelia Fluor 635
NB110-60017JF635
Janelia Fluor 646
NB110-60017JF646
Janelia Fluor 669
NB110-60017JF669
Unconjugated
NB110-60017
mFluor Violet 450 SE
NB110-60017MFV450
mFluor Violet 500 SE
NB110-60017MFV500
mFluor Violet 610 SE
NB110-60017MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-60017
Azide and BSA Free
NBP2-80700
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Dopamine D1R/DRD1 Antibody (SG2-D1a) [DyLight 680] Summary

Immunogen
Recombinant rat Dopamine Receptor D1 protein near the C-terminus. [Swiss-Prot# P18901]
Localization
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note: Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14.
Specificity
This antibody is specific for Dopamine Receptor D1A. There is no cross-reactivity with D1B (D5) receptor.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DRD1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry Free-Floating
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Dopamine D1R/DRD1 Antibody (SG2-D1a) [DyLight 680]

  • D(1A) dopamine receptor
  • D1DR
  • DADR
  • Dopamine D1 R
  • Dopamine D1 receptor
  • Dopamine D1R
  • dopamine receptor D1
  • DRD1
  • DRD1A

Background

The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DBD00
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NB110-60017FR
Dopamine D1R/DRD1 Antibody (SG2-D1a) [DyLight 680]
Species: Mu, Rt, Bv(-), Ca(-), Hu(-), Po(-), Rb(-), Sh(-)
Applications: WB, ICC/IF, IHC, IHC

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Bioinformatics

Gene Symbol DRD1