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DNA Polymerase epsilon subunit 3 Antibody (PCRP-POLE3-2F10) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, MA
Clone
PCRP-POLE3-2F10
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

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DNA Polymerase epsilon subunit 3 Antibody (PCRP-POLE3-2F10) [Biotin] Summary

Immunogen
Recombinant full-length human DNA Polymerase epsilon subunit 3 protein (Uniprot: Q9NRF9)
Localization
Nucleus, Cytoplasm
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
POLE3
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react in Mouse, Rat and Xenopus.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for DNA Polymerase epsilon subunit 3 Antibody (PCRP-POLE3-2F10) [Biotin]

  • Arsenic-transactivated protein
  • asTP
  • CHARAC17arsenic transactivated protein
  • CHRAC-17
  • CHRAC17Ybl1
  • Chromatin accessibility complex 17 kDa protein
  • DNA polymerase epsilon p17 subunit
  • DNA polymerase epsilon subunit 3
  • DNA polymerase epsilon subunit p17
  • DNA polymerase II subunit 3
  • EC 2.7.7.7
  • histone fold protein CHRAC17
  • huCHRAC17
  • p17
  • polymerase (DNA directed), epsilon 3 (p17 subunit)
  • YBL1

Background

DNA polymerase epsilon (POLE) is an enzyme that helps catalyze in the polymerization of deoxyribonucleotides into a DNA strand. The C-terminus of DNA polymerase E subunit complexes with subunits B and C, whereas the N-terminal domain contains an active polymerase domain.

DNA Pol E antibodies are useful for DNA replication and repair studies and in research on mitosis and cell replication.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol POLE3