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DMC1 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: DMC1 Antibody [NBP1-82838] - Analysis in human testis and pancreas tissues using NBP1-82838 antibody. Corresponding DMC1 RNA-seq data are presented for the ...read more
Immunohistochemistry-Paraffin: DMC1 Antibody [NBP1-82838] - Staining of human duodenum shows no expression in glandular cells as expected.
Immunohistochemistry-Paraffin: DMC1 Antibody [NBP1-82838] - Staining of human testis shows moderate nuclear positivity in a subset of cells in seminiferious ducts.
Immunohistochemistry-Paraffin: DMC1 Antibody [NBP1-82838] - Staining of human pancreas shows no expression in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: DMC1 Antibody [NBP1-82838] - Staining of human liver shows no expression in hepatocytes as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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DMC1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: AYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITA
Predicted Species
Mouse (100%), Rat (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DMC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
DMC1 Protein (NBP1-82838PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for DMC1 Antibody

  • disrupted meiotic cDNA1, yeast, homolog of
  • DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologousrecombination (yeast)
  • DMC1 homologue
  • HsLim15
  • LIM15yeast homolog) meiosis-specific homologousrecombination
  • meiotic recombination protein DMC1/LIM15 homolog
  • MGC150472
  • MGC150473

Background

DMC-1 is a meiosis-specific homologue of RecA/Rad51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes. DMC-1 is the human equivalent of e. coli recA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DMC1 Antibody (NBP1-82838) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for DMC1 Antibody (NBP1-82838)

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Blogs on DMC1.

Determining DMC1's role in Homologus Recombination
The DMC1 gene encodes a 36.7 kDa nuclear protein involved in meiotic homologous recombination. This recombinase is functionally related to the yeast RAD51 and E. coli RecA genes. In contrast to RAD51, which functions in both mitotic and meiotic recomb...  Read full blog post.

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Bioinformatics

Gene Symbol DMC1