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Desmoplakin Antibody (SR1430)

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Western Blot: Desmoplakin Antibody (SR1430) [NBP3-22092] - Western blot analysis using NBP3-22092 in A431 cell lysate.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, Flow, ICC/IF
Clone
SR1430
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Desmoplakin Antibody (SR1430) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Desmoplakin (Uniprot #: P15924)
Specificity
Detects endogenous levels of total Desmoplakin
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
DSP
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Western Blot 1:500-1:2000
Theoretical MW
270 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Desmoplakin Antibody (SR1430)

  • 250/210 kDa paraneoplastic pemphigus antigen
  • DCWHKTA
  • desmoplakin (DPI, DPII)
  • desmoplakin I
  • desmoplakin II
  • Desmoplakin
  • DP
  • DPI
  • DPII
  • DSP
  • KPPS2
  • PPKS2

Background

Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol DSP