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Dectin-1/CLEC7A Antibody (259931) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N, CyTOF-ready, ICC/IF
Clone
259931
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1859U-100UG
Alexa Fluor 405
FAB1859V-100UG
Alexa Fluor 488
FAB1859G-100UG
Alexa Fluor 532
FAB1859X
Alexa Fluor 594
FAB1859T-100UG
Alexa Fluor 647
FAB1859R-100UG
Alexa Fluor 700
FAB1859N-100UG
Alexa Fluor 750
FAB1859S-100UG
Allophycocyanin
FAB1859A-100
Allophycocyanin
FAB1859A-025
Allophycocyanin/Cy7
FAB1859APCCY7
Biotin
FAB1859B
DyLight 350
FAB1859D
DyLight 405
FAB1859E
DyLight 488
FAB1859K
DyLight 550
FAB1859L
DyLight 594
FAB1859M
DyLight 650
FAB1859W
DyLight 680
FAB1859Y
DyLight 755
FAB1859Z
HRP
FAB1859H
Janelia Fluor 525
FAB1859JF525
Janelia Fluor 549
FAB1859I
Janelia Fluor 646
FAB1859J
Janelia Fluor 669
FAB1859JF669
PE/Atto594
FAB1859PEATT594
PE/Cy5.5
FAB1859PECY55
PE/Cy7
FAB1859PECY7
Phycoerythrin
FAB1859P-025
Phycoerythrin
FAB1859P-100
Unconjugated
MAB1859
mFluor Violet 450 SE
FAB1859MFV450
mFluor Violet 500 SE
FAB1859MFV500
mFluor Violet 610 SE
FAB1859MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1859
Carrier Free
MAB1859
Carrier Free
MAB1859-SP
Carrier Free
FAB1859A-100
Carrier Free
FAB1859A-025
Carrier Free
FAB1859P-100
Carrier Free
FAB1859P-025
Carrier Free
FAB1859V-100UG
Carrier Free
FAB1859U-100UG
Carrier Free
FAB1859T-100UG
Carrier Free
FAB1859S-100UG
Carrier Free
FAB1859R-100UG
Carrier Free
FAB1859G-100UG
Carrier Free
FAB1859N-100UG
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Dectin-1/CLEC7A Antibody (259931) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Additional Information
Clone 259931 was used by HLDA to establish CD designation
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Dectin‑1/CLEC7A
Thr66-Met201
Accession # NP_072092
Specificity
Detects human Dectin‑1/CLEC7A in direct ELISAs. In directs ELISAs, less than 10% cross-reactivity with recombinant human (rh) DLEC and no cross-reactivity with recombinant mouse Dectin-1 or rhDectin-2 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CLEC7A
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Dectin-1/CLEC7A Antibody (259931) [CoraFluor™ 1]

  • Beta-glucan receptor
  • BGR
  • CD369
  • CLEC7A
  • CLECSF12
  • CLECSF12DC-associated C-type lectin 1
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12
  • C-type lectin domain family 7 member A
  • C-type lectin domain family 7, member A
  • C-type lectin superfamily member 12
  • Dectin1
  • Dectin-1
  • DECTIN1CANDF4
  • Dendritic cell-associated C-type lectin 1
  • dendritic cell-associated C-type lectin-1
  • hDectin-1
  • lectin-like receptor 1

Background

Dectin1 encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CLEC7A