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Dectin-1/CLEC7A Antibody (218820) [DyLight 755]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
218820
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB17561U-100UG
Alexa Fluor 405
FAB17561V-100UG
Alexa Fluor 488
FAB17561G-100UG
Alexa Fluor 532
FAB17561X
Alexa Fluor 594
FAB17561T-100UG
Alexa Fluor 647
FAB17561R-100UG
Alexa Fluor 700
FAB17561N
Alexa Fluor 750
FAB17561S-100UG
Allophycocyanin
FAB17561A
Allophycocyanin/Cy7
FAB17561APCCY7
Biotin
FAB17561B
CoraFluor 1
FAB17561CL1
DyLight 350
FAB17561D
DyLight 405
FAB17561E
DyLight 488
FAB17561K
DyLight 550
FAB17561L
DyLight 594
FAB17561M
DyLight 650
FAB17561W
DyLight 680
FAB17561Y
FITC
FAB17561F
HRP
FAB17561H
Janelia Fluor 525
FAB17561JF525
Janelia Fluor 549
FAB17561I
Janelia Fluor 585
FAB17561JF585
Janelia Fluor 635
FAB17561JF635
Janelia Fluor 646
FAB17561J
Janelia Fluor 669
FAB17561JF669
PE/Atto594
FAB17561PEATT594
PE/Cy5.5
FAB17561PECY55
PE/Cy7
FAB17561PECY7
Phycoerythrin
FAB17561P
Unconjugated
MAB17561
mFluor Violet 450 SE
FAB17561MFV450
mFluor Violet 500 SE
FAB17561MFV500
mFluor Violet 610 SE
FAB17561MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB17561
Carrier Free
FAB17561P
Carrier Free
MAB17561
Carrier Free
FAB17561A
Carrier Free
FAB17561N
Carrier Free
MAB17561-SP
Carrier Free
FAB17561V-100UG
Carrier Free
FAB17561U-100UG
Carrier Free
FAB17561T-100UG
Carrier Free
FAB17561S-100UG
Carrier Free
FAB17561R-100UG
Carrier Free
FAB17561G-100UG
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Dectin-1/CLEC7A Antibody (218820) [DyLight 755] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Dectin‑1/CLEC7A
Phe69-Leu244
Accession # Q6QLQ4
Specificity
Detects mouse Dectin‑1/CLEC7A in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Dectin-1 is observed and no cross-reactivity with recombinant mouse Dectin-2 or rhDLEC is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CLEC7A
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Dectin-1/CLEC7A Antibody (218820) [DyLight 755]

  • Beta-glucan receptor
  • BGR
  • CD369
  • CLEC7A
  • CLECSF12
  • CLECSF12DC-associated C-type lectin 1
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12
  • C-type lectin domain family 7 member A
  • C-type lectin domain family 7, member A
  • C-type lectin superfamily member 12
  • Dectin1
  • Dectin-1
  • DECTIN1CANDF4
  • Dendritic cell-associated C-type lectin 1
  • dendritic cell-associated C-type lectin-1
  • hDectin-1
  • lectin-like receptor 1

Background

Dectin1 encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CLEC7A