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Cytokeratin 6 Antibody (3F7A1)

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Western Blot: Cytokeratin 6 Antibody (3F7A1) [NBP3-15324] - Western blot analysis of extracts of various cell lines, using Cytokeratin 6 (KRT6) Rabbit mAb (NBP3-15324) at 1:1000 dilution. Secondary antibody: HRP Goat ...read more
Immunohistochemistry-Paraffin: Cytokeratin 6 Antibody (3F7A1) [NBP3-15324] - Immunohistochemistry of paraffin-embedded human esophageal using Cytokeratin 6 (KRT6) Rabbit mAb (NBP3-15324) at dilution of 1:100 (40x ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
3F7A1
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Cytokeratin 6 Antibody (3F7A1) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 465-564 of human Cytokeratin 6 (P48668). YRKLLEGEECRLNGEGVGQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KRT6A
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500 - 1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol, 0.05% BSA
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Cytokeratin 6 Antibody (3F7A1)

  • Allergen Hom s 5
  • CK6A
  • CK-6A
  • CK6C
  • CK6D
  • CK-6D
  • cytokeratin 6A
  • cytokeratin 6C
  • cytokeratin 6D
  • Cytokeratin-6A
  • Cytokeratin-6D
  • K6A
  • K6C
  • K6D
  • keratin 6A
  • keratin 6C
  • keratin 6D
  • keratin, epidermal type II, K6A
  • keratin, type II cytoskeletal 6A
  • Keratin-6A
  • KRT6C
  • KRT6D
  • Type-II keratin Kb6

Background

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77% of all forms found in epithelia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NBP3-15324

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Bioinformatics

Gene Symbol KRT6A