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Cytochrome b245 alpha Antibody (CS9) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, IHC, IP
Clone
CS9
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

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Cytochrome b245 alpha Antibody (CS9) [FITC] Summary

Immunogen
Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
Specificity
This antibody recognises the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterised by severe recurrent infections.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CYBA
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for Cytochrome b245 alpha Antibody (CS9) [FITC]

  • cytochrome b light chain
  • Cytochrome b(558) alpha chain
  • cytochrome b(558) alpha-subunit
  • cytochrome b, alpha polypeptide
  • cytochrome b-245 light chain
  • cytochrome b-245, alpha polypeptide
  • Cytochrome b558 subunit alpha
  • flavocytochrome b-558 alpha polypeptide
  • Neutrophil cytochrome b 22 kDa polypeptide
  • p22 phagocyte B-cytochrome
  • p22phox
  • p22-PHOX
  • Superoxide-generating NADPH oxidase light chain subunit

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CYBA