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CYP46A1 Antibody (N8-P6E4*H8) [Alexa Fluor® 532]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clone
N8-P6E4*H8
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 532

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CYP46A1 Antibody (N8-P6E4*H8) [Alexa Fluor® 532] Summary

Description
The clone number is listed as N8-P6E4*H8 in the scientific literature.
Immunogen
Ovalbumin-conjugated synthetic peptide- PVLCTLRPR (C-terminal sequence)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CYP46A1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CYP46A1 Antibody (N8-P6E4*H8) [Alexa Fluor® 532]

  • CH24H
  • cholesterol 24-hydroxylase
  • CYP46CP46
  • Cytochrome P450 46A1
  • cytochrome P450, family 46, subfamily A, polypeptide 1
  • cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
  • EC 1.14.13.98

Background

CYP46A1 (cytochrome P450, family 46, subfamily A, polypeptide 1) belongs to the cytochrome P450 family which consist of a variety of enzymes that are involved in catalyzing reactions. CYP46A1 is expressed in the brain and is involved in turnover of cholesterol through the conversion of cholesterol to 24S-hydroxycholesterol. CYP46A1 is known to have interactions with CH25H, CYP27A1, CYP39A1, CYP7A1 and CEL. Recent studies of CYP46A1 have been conducted in relation to Alzheimer's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CYP46A1