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CXCL8/IL-8 Antibody (6217) [mFluor Violet 610 SE]

 
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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Simple Western, B/N, CyTOF-ready, ELISA, ELISA(Cap), ELISA(Det), Flow, ICC/IF
Clone
6217
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB208U
Alexa Fluor 350
IC208U-100UG
Alexa Fluor 405
FAB208V
Alexa Fluor 405
IC208V-100UG
Alexa Fluor 488
IC208G-100UG
Alexa Fluor 488
FAB208G
Alexa Fluor 532
FAB208X
Alexa Fluor 594
IC208T-100UG
Alexa Fluor 594
FAB208T
Alexa Fluor 647
IC208R-100UG
Alexa Fluor 647
FAB208R
Alexa Fluor 700
FAB208N
Alexa Fluor 700
IC208N-100UG
Alexa Fluor 750
FAB208S
Alexa Fluor 750
IC208S-100UG
Allophycocyanin
FAB208A
Biotin
FAB208B
DyLight 350
FAB208D
DyLight 405
FAB208E
DyLight 488
FAB208K
DyLight 550
FAB208L
DyLight 594
FAB208M
DyLight 650
FAB208W
DyLight 680
FAB208Y
DyLight 755
FAB208Z
Fluorescein
IC208F
HRP
FAB208H
Janelia Fluor 549
FAB208I
Janelia Fluor 646
FAB208J
PerCP
FAB208C
Phycoerythrin
IC208P
Unconjugated
MAB208-100
mFluor Violet 450 SE
FAB208MFV450
mFluor Violet 500 SE
FAB208MFV500
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB208-100
Carrier Free
IC208F
Carrier Free
IC208P
Carrier Free
MAB208-SP
Carrier Free
MAB208-100
Carrier Free
MAB208-500
Carrier Free
IC208V-100UG
Carrier Free
IC208U-100UG
Carrier Free
IC208T-100UG
Carrier Free
IC208S-100UG
Carrier Free
IC208R-100UG
Carrier Free
IC208N-100UG
Carrier Free
IC208G-100UG
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CXCL8/IL-8 Antibody (6217) [mFluor Violet 610 SE] Summary

Immunogen
E. coli-derived recombinant human IL-8/CXCL8
Ser28-Ser99
Accession # P10145
Specificity
Detects human IL-8/CXCL8 in ELISAs and Western blots. In Western blots, 100% cross-reactivity with recombinant porcine IL-8/CXCL8 and no cross-reactivity with recombinant rat CXCL3/CINC-2 alpha is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL8
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Immunocytochemistry
  • Intracellular Staining by Flow Cytometry
  • Neutralization
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CXCL8/IL-8 Antibody (6217) [mFluor Violet 610 SE]

  • 3-10C
  • AMCF-I
  • C-X-C motif chemokine 8
  • CXCL8
  • CXCL8SCYB8
  • Emoctakin
  • GCP1
  • GCP-1TSG-1
  • IL8
  • IL-8
  • interleukin 8
  • K60
  • LAI
  • LECT
  • LUCT
  • LYNAP
  • MDNCF
  • MDNCFb-ENAP
  • member 8
  • MONAP
  • MONAPGCP1
  • NAF
  • NAP1
  • NAP-1NAP1
  • NCF
  • Neutrophil-activating protein 1
  • Protein 3-10C
  • T cell chemotactic factor
  • T-cell chemotactic factor
  • TCF
  • TSG1

Background

IL8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins are proinflammatory and primarily mediate the activation and migration of neutrophils into tissue from peripheral blood. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAB208MFV610
CXCL8/IL-8 Antibody (6217) [mFluor Violet 610 SE]
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mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol IL8