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CTDSP1 Antibody

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Immunocytochemistry/Immunofluorescence: CTDSP1 Antibody [NBP2-57578] - Staining of human cell line Hep G2 shows localization to nucleoplasm.
Immunocytochemistry/ Immunofluorescence: CTDSP1 Antibody [NBP2-57578] - Staining of human cell line Hep G2 shows localization to nucleoplasm.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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CTDSP1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVV
Predicted Species
Mouse (95%), Rat (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CTDSP1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
CTDSP1 Recombinant Protein Antigen (NBP2-57578PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for CTDSP1 Antibody

  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 1
  • NIF3
  • NLI-IF
  • NLIIFEC 3.1.3.16
  • NLI-interacting factor 3
  • SCP1Nuclear LIM interactor-interacting factor 3
  • Small CTD phosphatase 1
  • Small C-terminal domain phosphatase 1

Background

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation.Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronalcells

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CTDSP1