Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Ca
Applications: ELISA, IHC
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation.Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronalcells
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
58190 |
| Alternate Names |
- carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
- CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 1
- NIF3
- NLI-IF
- NLIIFEC 3.1.3.16
- NLI-interacting factor 3
- SCP1Nuclear LIM interactor-interacting factor 3
- Small CTD phosphatase 1
- Small C-terminal domain phosphatase 1
|
