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CTDSP1 Antibody (OTI1B6) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clone
OTI1B6
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

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CTDSP1 Antibody (OTI1B6) [Janelia Fluor® 549] Summary

Immunogen
Full length recombinant protein of human CTDSP1 (NP_067021) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CTDSP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CTDSP1 Antibody (OTI1B6) [Janelia Fluor® 549]

  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 1
  • NIF3
  • NLI-IF
  • NLIIFEC 3.1.3.16
  • NLI-interacting factor 3
  • SCP1Nuclear LIM interactor-interacting factor 3
  • Small CTD phosphatase 1
  • Small C-terminal domain phosphatase 1

Background

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation.Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronalcells

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CTDSP1