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CRX/CORD2 Antibody

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Independent Antibodies: Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88060] - Staining of human cerebral cortex, colon, eye, retina and testis using Anti-CRX antibody NBP1-88060 (A) shows similar ...read more
Western Blot: CRX/CORD2 Antibody [NBP1-88060] - Analysis in control (vector only transfected HEK293T lysate) and CRX over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T ...read more
Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88060] - Staining of human cerebral cortex.
Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88060] - Staining of human placenta shows no positivity in trophoblastic cells as expected.
Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88060] - Staining of human retina shows moderate nuclear positivity in outer nuclear layer (rod and cone cell bodies).
Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88060] - Staining of human eye, retina.
Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88060] - Staining of human colon.
Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88060] - Staining of human testis.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

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CRX/CORD2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: PLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYGAYSPVDSLEFK
Predicted Species
Mouse (97%), Rat (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRX
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
CRX/CORD2 Protein (NBP1-88060PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for CRX/CORD2 Antibody

  • cone-rod homeobox
  • CORD2
  • CRDcone-rod homeobox protein
  • CRX
  • LCA7
  • LCA7orthodenticle homeobox 3
  • OTX3

Background

CORD2 is encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CRX