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COX-2 Antibody (COX2/3320R) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
COX2/3320R
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

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COX-2 Antibody (COX2/3320R) [Janelia Fluor® 525] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Synthetic peptide corresponding to COX-2 residues within aa504-604 of COX-2 (Uniprot: P35354)
Localization
Cytoplasm, Cell surface
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PTGS2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for COX-2 Antibody (COX2/3320R) [Janelia Fluor® 525]

  • COX2
  • COX-2
  • COX2cyclooxygenase 2b
  • cyclooxygenase-2
  • EC 1.14.99
  • EC 1.14.99.1
  • GRIPGHS
  • hCox-2
  • PGG/HS
  • PGH synthase 2
  • PGHS-2
  • PHS II
  • PHS-2
  • PHS-II
  • prostaglandin G/H synthase 2
  • prostaglandin G/H synthase and cyclooxygenase
  • Prostaglandin H2 synthase 2
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase andcyclooxygenase)
  • Prostaglandin-endoperoxide synthase 2
  • PTGS2

Background

COX2 (Cyclooxygenase 2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Research Areas for COX-2 Antibody (NBP3-08301JF525)

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SUCNR1/GPR91 - a potential role in renovascular hypertension
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Inhibitor kappa B-alpha (IkappaB-alpha)
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Bioinformatics

Gene Symbol PTGS2