COP9 signalosome complex subunit 2 Antibody Summary
Immunogen |
Peptide with sequence C-LNSLNQAVVSKLA corresponding to C-Terminus according to NP_001137359.1. |
Predicted Species |
Rat (100%), Canine (100%), Bovine (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
COPS2 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 3 - 5 ug/ml
- Immunohistochemistry-Paraffin 3 - 5 ug/ml
- Peptide ELISA Detection limit 1:16000
- Western Blot 1 - 3 ug/ml
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Application Notes |
WB: Approx. 48 kDa band observed in human brain, mouse brain lysates and in lysates of mouse putuitary cell line NIH3T3 (calculated MW of 51.6 kDa band according to NP_004227.1). IHC-P: Human thyroid gland shows nclear and cytoplasm staining in activated epithelial cells |
Control |
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Publications |
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Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA |
Preservative |
0.02% Sodium Azide |
Concentration |
0.5 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for COP9 signalosome complex subunit 2 Antibody
Background
TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for COP9 signalosome complex subunit 2 Antibody (NB100-1238)(2)
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FAQs for COP9 signalosome complex subunit 2 Antibody (NB100-1238) (0)
Control Lysate(s)
Secondary Antibodies
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Isotype Controls
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