Human peripheral blood granulocytes were stained with Mouse Anti-Human Complement Component C5a R1 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB3648F, filled histogram) or isotype control antibody (Catalog # ...read more
12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Complement Component C5aR1 Antibody (347214) [Fluorescein]
C5a anaphylatoxin chemotactic receptor
C5A
C5aR
C5a-R
C5AR1
C5ARC5a anaphylatoxin receptor
C5R1C5a ligand
CD88 antigen
CD88
complement component 5 receptor 1 (C5a ligand)
complement component 5 receptor 1
complement component 5a receptor 1
Complement Component C5a R1
Complement Component C5aR1
Background
Complement Component C5a R1 (C5aR1), also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5aR binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of proinflammatory mediators. In contrast, C5aR1/C5a interactions are protective during allergen sensitization. Human C5aR1 shares 66% amino acid sequence identity with mouse and rat C5aR.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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