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Complement Component C5aR1 Antibody (347214) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
347214
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3648U-100UG
Alexa Fluor 405
FAB3648V-100UG
Alexa Fluor 488
FAB3648G-100UG
Alexa Fluor 532
FAB3648X
Alexa Fluor 594
FAB3648T-100UG
Alexa Fluor 647
FAB3648R-100UG
Alexa Fluor 700
FAB3648N-100UG
Alexa Fluor 750
FAB3648S-100UG
Allophycocyanin
FAB3648A
Allophycocyanin/Cy7
FAB3648APCCY7
Biotin
FAB3648B
CoraFluor 1
FAB3648CL1
DyLight 350
FAB3648D
DyLight 488
FAB3648K
DyLight 550
FAB3648L
DyLight 594
FAB3648M
DyLight 650
FAB3648W
DyLight 680
FAB3648Y
DyLight 755
FAB3648Z
Fluorescein
FAB3648F
HRP
FAB3648H
Janelia Fluor 525
FAB3648JF525
Janelia Fluor 549
FAB3648I
Janelia Fluor 585
FAB3648JF585
Janelia Fluor 635
FAB3648JF635
Janelia Fluor 646
FAB3648J
Janelia Fluor 669
FAB3648JF669
PE/Atto594
FAB3648PEATT594
PE/Cy5.5
FAB3648PECY55
PE/Cy7
FAB3648PECY7
PerCP
FAB3648C
Phycoerythrin
FAB3648P
Unconjugated
MAB3648
mFluor Violet 450 SE
FAB3648MFV450
mFluor Violet 500 SE
FAB3648MFV500
mFluor Violet 610 SE
FAB3648MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3648
Carrier Free
FAB3648F
Carrier Free
FAB3648P
Carrier Free
MAB3648
Carrier Free
FAB3648A
Carrier Free
MAB3648-SP
Carrier Free
FAB3648V-100UG
Carrier Free
FAB3648U-100UG
Carrier Free
FAB3648T-100UG
Carrier Free
FAB3648S-100UG
Carrier Free
FAB3648R-100UG
Carrier Free
FAB3648N-100UG
Carrier Free
FAB3648G-100UG
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Complement Component C5aR1 Antibody (347214) [DyLight 405] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Complement Component C5a R1
Met1-Val350
Accession # P21730
Specificity
Detects human Complement Component C5a R1. Stains human Complement Component C5a R1 transfected cells but not irrelevant transfectants.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
C5AR1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Complement Component C5aR1 Antibody (347214) [DyLight 405]

  • C5a anaphylatoxin chemotactic receptor
  • C5A
  • C5aR
  • C5a-R
  • C5AR1
  • C5ARC5a anaphylatoxin receptor
  • C5R1C5a ligand
  • CD88 antigen
  • CD88
  • complement component 5 receptor 1 (C5a ligand)
  • complement component 5 receptor 1
  • complement component 5a receptor 1
  • Complement Component C5a R1
  • Complement Component C5aR1

Background

The human anaphylatoxin C5a is a 74 residue glycopeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a can be demonstrated, rendering this molecule an important mediartor of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP binding coupled receptor that belongs to the rhodopsin supergene family. C5a receptor 1 expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. ESTs have been isolated from B cell/lung/testis, nerve, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C5AR1