Recombinant Rat CNTF Protein

Ciliary neurotrophic factor (CNTF) is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. CNTF was initially identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. Furthermore, the protein is also a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition, CNTF is useful for treatment of motor neuron disease and it could reduce food intake without causing hunger or stress Recombinant rat CNTF containing 199 amino acids and it shares 83 % and 95 % a.a. sequence identity with human and murine CNTF.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using NBP2-35289	Applications	Species
Uchida T, Ueta T, Honjo M, Aihara M The Neuroprotective Effect of the Adiponectin Receptor Agonist AdipoRon on Glutamate-Induced Cell Death in Rat Primary Retinal Ganglion Cells J Ocul Pharmacol Ther 2019-08-28 [PMID: 31460821]

Array NBP2-35289

• CNTF Antibodies
• CNTF ELISA Kits
• CNTF Lysate
• CNTF Proteins
• CNTF ELISAs
• CNTF Proteins and Enzymes