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Claudin-8 Antibody (474210) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, Flow
Clone
474210
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

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Claudin-8 Antibody (474210) [Janelia Fluor® 585] Summary

Immunogen
HEK293 human embryonic kidney cell line transfected with human Claudin-8
Met1-Val225 (Ser151Pro)
Accession # P56748
Specificity
Detects human Claudin‑8. Stains human Claudin-8 transfectants but not irrelevant transfectants.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CLDN8
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Intracellular Staining by Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Claudin-8 Antibody (474210) [Janelia Fluor® 585]

  • claudin 8
  • Claudin8
  • Claudin-8
  • CLDN8
  • human CLDN8 gene for claudin-810claudin-8

Background

Claudins, such as CLDN8, are components of epithelial cell tight junctions. Tight junctions regulate movement of solutes and ions through the paracellular space and prevent mixing of proteins and lipids in the outer leaflet of the apical and basolateral plasma membrane domains (Acharya et al., 2004).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CLDN8