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CHN 1 Antibody (OTI2G6)

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Western Blot: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CHN 1.
Immunocytochemistry/ Immunofluorescence: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY CHN 1.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human prostate tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Carcinoma of Human kidney tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Carcinoma of Human thyroid tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Adenocarcinoma of Human ovary tissue using CHN1 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human Kidney tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Adenocarcinoma of Human breast tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human lymphoma tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human breast tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Adenocarcinoma of Human colon tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Carcinoma of Human bladder tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human liver tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Adenocarcinoma of Human endometrium tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Carcinoma of Human prostate tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human pancreas tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human colon tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Carcinoma of Human liver.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human lung tissue.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Carcinoma of Human lung tissue.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
OTI2G6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

CHN 1 Antibody (OTI2G6) Summary

Immunogen
Full length human recombinant protein of human CHN1(NP_001813) produced in HEK293T cell.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CHN1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150
  • Western Blot 1:2000
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CHN 1 Antibody (OTI2G6)

  • a2-chimaerin
  • A-chimaerin
  • alpha-chimerin
  • ARHGAP2RhoGAP2
  • chimerin (chimaerin) 1
  • CHNDuane retraction syndrome 2
  • DURS2
  • NC
  • N-chimaerin
  • n-chimerin
  • Rho GTPase-activating protein 2
  • RHOGAP2

Background

CHN 1 encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane's retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CHN 1 Antibody (NBP2-46290) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol CHN1