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CEACAM6/CD66c Antibody (1H7-4B) - BSA Free

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Immunohistochemistry: CEACAM-6/CD66c Antibody (1H7-4B) [NBP2-54626] - Analysis in human lung: Using Anti-CEACAM6 [1H7-4B] (10 ug/ml) developed with DAB-staining procedure. Dark line indicated shows CEACAM6 expression.
Flow Cytometry: CEACAM-6/CD66c Antibody (1H7-4B) [NBP2-54626] - Binding of 10 ug/ml primary positive control mAb (upper panel), Anti-CEACAM6 [1H7-4B] (lower panel), negative isotype matched control mAb (thin line) on ...read more
ELISA: CEACAM-6/CD66c Antibody (1H7-4B) [NBP2-54626] - Solid phase was coated with 3 ug/ml Anti-CEA binding human CEACAM1-CEACAM8. After washing, blocking and coating human CEACAM1 antigen, detecting antibody ...read more
Immunoprecipitation: CEACAM-6/CD66c Antibody (1H7-4B) [NBP2-54626] - Human granulocyte lysate: Utilizing 10 ug/ml Anti-CEACAM6 [1H7-4B]. Detection of the sample using 5 ug/ml pAb Anti-CEA followed by HRP-coupled ...read more
Western Blot: CEACAM-6/CD66c Antibody (1H7-4B) [NBP2-54626] - Detection using 10 μg/ml NBP2-54626 followed by HRP-coupled secondary antibody. Visualized by Chemiluminescence detection.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, Flow, IHC, CyTOF-ready
Clone
1H7-4B
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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CEACAM6/CD66c Antibody (1H7-4B) - BSA Free Summary

Immunogen
Recombinant human CEACAM6/CD66c extracellular domain.
Specificity
Clone 1H7-4B does not cross-react with human CEACAM1/3/4/5/7/8, rat CECAM1, or mouse CEACAM1/2.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CEACAM6
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA 1:100 - 1:2000
  • Flow Cytometry 1:10 - 1 - 1000
  • Immunohistochemistry 1:100 - 1:500
  • Western Blot 1:100 - 1:2000
Application Notes
This antibody is CyTOF ready.
Theoretical MW
90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP2-54626.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID:32031201).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for CEACAM6/CD66c Antibody (1H7-4B) - BSA Free

  • carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific crossreacting antigen)
  • carcinoembryonic antigen-related cell adhesion molecule 6
  • CD66c antigen
  • CD66c
  • CEACAM6
  • CEACAM-6
  • CEAL
  • NCA
  • NCACEAL
  • Non-specific crossreacting antigen
  • Normal cross-reacting antigen

Background

CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glycoprotein (PSG1-PSG11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. CEACAM 6 expression is strongly up-regulated already during early stages of adenocarcinoma formation e.g. in colon. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CEACAM6/CD66c Antibody (NBP2-54626)(1)

We have publications tested in 1 confirmed species: Mouse.


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Bioinformatics

Gene Symbol CEACAM6