Home » CEACAM6/CD66c » CEACAM6/CD66c Antibodies » CEACAM6/CD66c Antibody (1H7-4B) [CoraFluor™ 1]
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CEACAM6/CD66c Antibody (1H7-4B) [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, Flow, IHC, CyTOF-ready
Clone
1H7-4B
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-54626AF350
Alexa Fluor 405
NBP2-54626AF405
Alexa Fluor 488
NBP2-54626AF488
Alexa Fluor 532
NBP2-54626AF532
Alexa Fluor 594
NBP2-54626AF594
Alexa Fluor 647
NBP2-54626AF647
Alexa Fluor 700
NBP2-54626AF700
Alexa Fluor 750
NBP2-54626AF750
Allophycocyanin
NBP2-54626APC
Biotin
NBP2-54626B
DyLight 350
NBP2-54626UV
DyLight 405
NBP2-54626V
DyLight 488
NBP2-54626G
DyLight 550
NBP2-54626R
DyLight 594
NBP2-54626DL594
DyLight 650
NBP2-54626C
DyLight 680
NBP2-54626FR
DyLight 755
NBP2-54626IR
FITC
NBP2-54626F
HRP
NBP2-54626H
Janelia Fluor 525
NBP2-54626JF525
Janelia Fluor 549
NBP2-54626JF549
Janelia Fluor 585
NBP2-54626JF585
Janelia Fluor 635
NBP2-54626JF635
Janelia Fluor 646
NBP2-54626JF646
Janelia Fluor 669
NBP2-54626JF669
PE
NBP2-54626PE
PerCP
NBP2-54626PCP
Unconjugated
NBP2-54626
mFluor Violet 450 SE
NBP2-54626MFV450
mFluor Violet 500 SE
NBP2-54626MFV500
mFluor Violet 610 SE
NBP2-54626MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-54626
BSA Free
NBP2-54626
BSA Free
NBP2-54626-0.025mg
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CEACAM6/CD66c Antibody (1H7-4B) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Recombinant human CEACAM6/CD66c extracellular domain.
Specificity
Clone 1H7-4B does not cross-react with human CEACAM1/3/4/5/7/8, rat CECAM1, or mouse CEACAM1/2.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CEACAM6
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID:32031201).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for CEACAM6/CD66c Antibody (1H7-4B) [CoraFluor™ 1]

  • carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific crossreacting antigen)
  • carcinoembryonic antigen-related cell adhesion molecule 6
  • CD66c antigen
  • CD66c
  • CEACAM6
  • CEACAM-6
  • CEAL
  • NCA
  • NCACEAL
  • Non-specific crossreacting antigen
  • Normal cross-reacting antigen

Background

CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glycoprotein (PSG1-PSG11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. CEACAM 6 expression is strongly up-regulated already during early stages of adenocarcinoma formation e.g. in colon. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CEACAM6