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Cdk7 Antibody (BL-80-5D4)

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Western Blot: Cdk7 Antibody (BL-80-5D4) [NBP2-76409] - Detection of human CDK7 by WB of HeLa, HEK293T, Jurkat, MCF-7, Hep-G2, A-549, SW620, SK-MEL-28 (SK), and HCT 116 lysate. Antibody: Rabbit anti-CDK7 recombinant ...read more
Immunocytochemistry: Cdk7 Antibody (BL-80-5D4) [NBP2-76409] - Detection of human CDK7 in FFPE breast carcinoma cell line MCF-7 by ICC. Antibody: Rabbit anti-CDK7 recombinant monoclonal [BL-80-5D4] (NBP2-76409). ...read more
Immunohistochemistry: Cdk7 Antibody (BL-80-5D4) [NBP2-76409] - Detection of human CDK7 in FFPE human ovarian carcinoma by IHC. Antibody: Rabbit anti-CDK7 recombinant monoclonal [BL-80-5D4] (NBP2-76409). Secondary: ...read more
Flow Cytometry: Cdk7 Antibody (BL-80-5D4) [NBP2-76409] - Detection of human CDK7 in MOLT4 cells by flow cytometry. Antibody: Rabbit anti-CDK7 recombinant monoclonal [BL-80-3D4] NBP2-76409 (red shaded) or isotype control ...read more
Immunoprecipitation: Cdk7 Antibody (BL-80-5D4) [NBP2-76409] - Detection of human CDK7 by WB of immunoprecipitates from HeLa lysate. Antibodies: Rabbit anti-CDK7 recombinant monoclonal [BL-80-5D4] (NBP2-76409).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, IP, ICC/IF
Clone
BL-80-5D4
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Cdk7 Antibody (BL-80-5D4) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Immunogen sequence between amino acids 300 and 3416 (C-Term)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CDK7
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry 1:50 - 1:200
  • Immunohistochemistry 1:25 - 1:100
  • Immunoprecipitation 20 ul/0.5 mg lysate
  • Western Blot 1:1000

Packaging, Storage & Formulations

Storage
Store at 2 - 8 C / 1 year from date of receipt
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Antigen Affinity-purified

Notes

This Product sold under License from Bethyl Laboratories, Inc.

Alternate Names for Cdk7 Antibody (BL-80-5D4)

  • CAK1Xenopus laevis, cdk-activating kinase)
  • Cdk7
  • CDK-activating kinase
  • CDKN7
  • Cell division protein kinase 7
  • cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
  • cyclin-dependent kinase 7
  • EC 2.7.11
  • EC 2.7.11.22
  • EC 2.7.11.23
  • EC 2.7.11.24
  • MO15
  • p39 Mo15
  • serine/threonine kinase stk1,39 kDa protein kinase
  • serine/threonine protein kinase 1
  • serine/threonine protein kinase MO15
  • STK1
  • TFIIH basal transcription factor complex kinase subunit

Background

Cyclin-dependent kinase 7 (CDK7) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK7 is the catalytic subunit in a trimeric complex with cyclin H and MAT1 that functions as a Cdk-activating kinase (CAK). CDK7 activates the kinase activities of CDK1, CDK2, CDK4, and CDK6 by threonine phosphorylation. In addition to its cell cycle function CDK7 has also been found to be an essential component of the transcription factor TFIIH. Several substrates of CDK7 are involved in transcription, further indicating a role in transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CDK7