Cdk7 Antibody (BL-80-5D4) Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Immunogen sequence between amino acids 300 and 3416 (C-Term) |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
CDK7 |
Purity |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry
- Immunocytochemistry 1:50 - 1:200
- Immunohistochemistry 1:25 - 1:100
- Immunoprecipitation 20 ul/0.5 mg lysate
- Western Blot 1:1000
|
Packaging, Storage & Formulations
Storage |
Store at 2 - 8 C / 1 year from date of receipt |
Buffer |
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA |
Preservative |
0.09% Sodium Azide |
Purity |
Antigen Affinity-purified |
Notes
This Product sold under License from Bethyl Laboratories, Inc.
Alternate Names for Cdk7 Antibody (BL-80-5D4)
Background
Cyclin-dependent kinase 7 (CDK7) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK7 is the catalytic subunit in a trimeric complex with cyclin H and MAT1 that functions as a Cdk-activating kinase (CAK). CDK7 activates the kinase activities of CDK1, CDK2, CDK4, and CDK6 by threonine phosphorylation. In addition to its cell cycle function CDK7 has also been found to be an essential component of the transcription factor TFIIH. Several substrates of CDK7 are involved in transcription, further indicating a role in transcription.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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