Cdk6 Antibody (8H4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 4 of 4.

Publications using H00001021-M01	Applications	Species
Xinjie B, Gengchao W, Shan Y et al. Transcriptomic analysis identifies a tumor subtype mRNA classifier for invasive non-functioning pituitary neuroendocrine tumor diagnostics. Theranostics. 2021-01-01 [PMID: 33391466]
Shuyan L, Tae S, Marina A et al. Phenotypic Characterization of Targeted Knockdown of Cyclin-Dependent Kinases in the Intestinal Epithelial Cells. Toxicol Sci. 2020-09-01 [PMID: 32556214]
Erdmann K, Kaulke K, Rieger C et al. MiR-26a and miR-138 block the G1/S transition by targeting the cell cycle regulating network in prostate cancer cells. J Cancer Res Clin Oncol 2016-08-25 [PMID: 27562865]
Quinn J, Glassford J, Percy L et al. APRIL promotes cell-cycle progression in primary multiple myeloma cells: influence of D-type cyclin group and translocation status. Blood. 2010-08-13 [PMID: 20709908]

Array H00001021-M01

• Cdk6 Antibodies
• Cdk6 ELISA Kit
• Cdk6 Lysates
• Cdk6 Proteins