Reactivity | HuSpecies Glossary |
Applications | Flow |
Clone | 423524 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Alexa Fluor 488 |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
Immunogen | NS0 mouse myeloma cell line transfected with human CD82/Kai‑1 Met1-Tyr267 Accession # AAH01821 |
Specificity | Detects human CD82/Kai‑1. Stains human CD82/Kai‑1 transfectants but not irrelevant transfectants. |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | CD82 |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells. |
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Reviewed Applications |
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Storage | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Buffer | Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
Preservative | 0.09% Sodium Azide |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
CD82, also known as KAI1, C33 and TSPAN27, is a widely expressed palmitoylated molecule in the tetraspanin superfamily. CD82 is synthesized as a 28 kDa core protein with mature molecular weights ranging up to 70 kDa due to variable glycosylation. CD82 functions as a suppressor of metastasis and is down‑regulated in many malignant tumors. It associates with IGSF8, DARC, the ganglioside GM2, and the HTLV-1 Gag protein. CD82 inhibits cell migration and metastasis by preventing integrin maturation and blocking integrin interactions with Met. Human CD82 shares 76% aa sequence identity with mouse and rat CD82.
Images | Ratings | Applications | Species | Date | Details | ||||||||
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reviewed by:
Craig Dorrell |
Flow | Human | 01/04/2016 |
Summary
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Secondary Antibodies |
Isotype Controls |
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