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CD37 Antibody (MB-1) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clone
MB-1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

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CD37 Antibody (MB-1) [DyLight 350] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
BALB/c mice were immunized with lymph node cells from a patient with nodular poorly differentiated lymphocytic lymphoma. Immunophenotyping studies of these cells identified them as B cells expressing SIgG/lambda, as well as HLA-DR. Leu-12, and B1.
Specificity
This antibody is specific for human CD37, which is expressed on virtually all mature B lymphocytes, but not on pro-B or plasma cells. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 does not appear to be expressed on T cells, thymocytes, granulocytes or platelets.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD37
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD37 Antibody (MB-1) [DyLight 350]

  • CD37 antigentetraspanin-26
  • CD37 molecule
  • CD37
  • cell differentiation antigen 37
  • GP52-40
  • leukocyte antigen CD37
  • MGC120234
  • Tetraspanin-26
  • TSPAN26
  • tspan-26
  • TSPAN26leukocyte surface antigen CD37

Background

CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD37