Caspr2 Antibody

Caspr2 encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with potassium channels. It may play a role in the local differentiation of the axon into distinct functional subdomains. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP1-88182	Applications	Species
Krumbiegel M, Pasutto F, Schlotzer-Schrehardt U et al. Genome-wide association study with DNA pooling identifies variants at CNTNAP2 associated with pseudoexfoliation syndrome. Eur J Hum Genet 2011-02-01 [PMID: 20808326]

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: YONGJIE LAI	WB	Human	09/24/2014	View Summary Application Western Blot Sample Tested Caspr2 plasmid transfected HEK293T cell lysate Species Human

Array NBP1-88182

• Caspr2 Antibodies
• Caspr2 ELISA Kit
• Caspr2 Lysate
• Caspr2 Protein
• Caspr2 Proteins and Enzymes