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CASK Antibody [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Simple Western, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 500 SE

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Protocols & FAQs
Support & Research

CASK Antibody [mFluor Violet 500 SE] Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CASK. The immunogen is located within amino acids 760 - 810 of CASK. Amino Acid Squence: YPIPHTTRPPKKDEENGKN
Specificity
At least six alternatively spliced transcript variants have been observed.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CASK
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CASK Antibody [mFluor Violet 500 SE]

  • calcium/calmodulin-dependent serine protein kinase (MAGUK family)
  • calcium/calmodulin-dependent serine protein kinase membrane-associatedguanylate kinase
  • Calcium/calmodulin-dependent serine protein kinase
  • CAMGUK
  • CMG
  • EC 2.7.11
  • EC 2.7.11.1
  • FGS4CAGH39
  • FLJ22219
  • hCASK
  • LIN2FLJ31914
  • MICPCH
  • peripheral plasma membrane protein CASK
  • Protein lin-2 homolog
  • TNRC8
  • trinucleotide repeat containing 8

Background

Calmodulin sensitive kinase (CASK/mLIN-2) is a ~112-kDa member of the membrane associated quanylate kinase (MAGUK) protein family with multiple protein binding domains. These include an N-terminal calmodulin kinase (CaMKII) domain and C-terminal PDZ, SH3-, and quanylate kinase domains. CASK possesses both tyrosine kinase and serine/threonine kinase activity. In addition, CASK can form a heterotrimeric complex with Mint (X11or mLIN-10) and Veli (mLIN-7) proteins which is predicted to participate in plasma membrane receptor localization. CASK is localized to neuronal synapses and also interacts with syndecan and neurexin. The guanylate kinase domain of CASK has been shown to interact with the T-box transcription factor, Tbr-1, as a coactivator to induce transcription of genes that contain T-elements.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CASK