Western Blot: CaM Kinase II alpha Antibody [NB100-81830] - Analysis of extracts from Hela using NB100-81830
Immunohistochemistry-Paraffin: CaM Kinase II alpha Antibody [NB100-81830] - Staining of paraffin-embedded human hippocampal region tissue from the falling sickness disease using NB100-81830
Western Blot: CaM Kinase II alpha Antibody [NB100-81830] - Western blotting analysis using NB100-81830
Use in Immunohistochemistry-paraffin reported in scientific literature (PMID: 28912554).
Theoretical MW
50 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified
Alternate Names for CaM Kinase II alpha Antibody
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
calcium/calmodulin-dependent protein kinase II alpha
calcium/calmodulin-dependent protein kinase II alpha-B subunit
CaM kinase II alpha subunit
CaM Kinase II alpha
CaM kinase II subunit alpha
CAMK2A
CAMKAcalcium/calmodulin-dependent protein kinase type II subunit alpha
CaMK-II alpha subunit
CaMK-II subunit alpha
CaMKIINalpha
CaM-kinase II alpha chain
EC 2.7.11
EC 2.7.11.17
KIAA0968calcium/calmodulin-dependent protein kinase type II alpha chain
Background
CaMKII (Calcium/calmodulin-dependent protein kinase II) is a ubiquitous serine/threonine protein kinase that is abundant in the brain as a major constituent of the postsynaptic density (PSD). The enzyme is an oligomeric protein composed of distinct but related subunits, alpha, beta, gamma, and delta, each encoded by a separate gene. CAMK2A assembles into heterooligomeric complexes with other CAMK2 subunits. CaMKII is a prominent kinase in the central nervous system that may function in long term potentiation and neurotransmitter release.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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