Caldesmon/CALD1 Antibody

Caldesmon is a smooth muscle and nonmuscle regulatory protein that interacts with actin, myosin, tropomyosin, and calmodulin (1,2). Smooth muscle caldesmon is an elongated molecule with a calmodulin, tropomyosin, and actin-binding region at the C-terminus and a myosin-binding domain at the N-terminus (3). Caldesmon stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, caldesmon inhibits the actomyosin ATPase by binding to F-actin. This inhibition is reduced by calcium-calmodulin and is promoted by tropomyosin (4).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using NBP1-85701	Applications	Species
Andersson S, Konrad A, Ashok N et al. Antibodies Biotinylated Using a Synthetic Z-domain from Protein A Provide Stringent In Situ Protein Detection. J Histochem Cytochem 2013-11-01 [PMID: 23920108]
Qundos U, Hong MG, Tybring G et al. Profiling post-centrifugation delay of serum and plasma with antibody bead arrays. J Proteomics 2013-12-16 [PMID: 23631827]
Kohler CN, et al. Histochemical localization of caldesmon in the CNS and ganglia of the mouse. J Histochem Cytochem 2011-05-01 [PMID: 21411712]

Array NBP1-85701

• Caldesmon/CALD1 Antibodies
• Caldesmon/CALD1 ELISA Kits
• Caldesmon/CALD1 Proteins