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Cadherin-17 Antibody

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Orthogonal Strategies: Western Blot: Cadherin-17 Antibody [NBP1-88237] - Analysis in human cell lines Caco-2 and SK-MEL-30 using anti-CDH17 antibody. Corresponding CDH17 RNA-seq data are presented for the same ...read more
Immunohistochemistry-Paraffin: Cadherin-17 Antibody [NBP1-88237] - Analysis in human duodenum and liver tissues using NBP1-88237 antibody. Corresponding Cadherin-17 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Cadherin-17 Antibody [NBP1-88237] - Staining of human kidney.
Immunohistochemistry-Paraffin: Cadherin-17 Antibody [NBP1-88237] - Staining of human colon.
Immunohistochemistry-Paraffin: Cadherin-17 Antibody [NBP1-88237] - Staining of human duodenum using Anti-CDH17 antibody NBP1-88237.
Immunohistochemistry-Paraffin: Cadherin-17 Antibody [NBP1-88237] - Staining of human liver using Anti-CDH17 antibody NBP1-88237.
Independent Antibodies: Staining of human colon, duodenum, kidney and liver using NBP1-88237 (A) shows similar protein distribution across tissues to independent antibody NBP1-88239 (B).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Cadherin-17 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: GTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CDH17
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot 0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Cadherin-17 Protein (NBP1-88237PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (80%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Cadherin-17 Antibody

  • cadherin 17, LI cadherin (liver-intestine)
  • cadherin
  • cadherin-16
  • Cadherin17
  • Cadherin-17
  • CDH16
  • CDH17
  • FLJ26931
  • HPT-1 cadherin
  • HPT1
  • HPT-1
  • human intestinal peptide-associated transporter HPT-1
  • human peptide transporter 1
  • Intestinal peptide-associated transporter HPT-1
  • LI cadherin
  • LI-cadherin
  • Liver-intestine cadherin
  • MGC138218
  • MGC142024

Background

LI Cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CDH17