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CACNA1E Antibody

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ICC/IF, IHC, IP, NULL
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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CACNA1E Antibody Summary

Immunogen
Immunized with recombinant Mouse CACNA1E (Uniprot#: Q61290; Gly246~Trp327)
Clonality
Polyclonal
Host
Rabbit
Gene
CACNA1E
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20 ug/mL
  • Immunohistochemistry 5-20 ug/mL
  • Immunoprecipitation
  • Serum
  • Western Blot 0.2-2 ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH7.4, 50% glycerol.
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for CACNA1E Antibody

  • BII
  • Brain calcium channel II
  • CACH6
  • CACH6calcium channel, R type, alpha-1 polypeptide
  • CACNA1E
  • CACNL1A6
  • CACNL1A6calcium channel, voltage-dependent, alpha 1E subunit
  • calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Cav2.3
  • L type, alpha-1 polypeptide
  • L type, alpha-1 polypeptide, isoform 6
  • voltage-dependent calcium channel alpha 1E subunit
  • voltage-dependent R-type calcium channel subunit alpha-1E
  • voltage-gated calcium channel alpha 1E subunit
  • Voltage-gated calcium channel subunit alpha Cav2.3

Background

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels contaning alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.; Subcellular location: Membrane; Multi-pass membrane protein.; Tissue specificity: Expressed in neuronal tissues and in kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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ICC/IF Video Protocol

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Array NBP3-43404

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Bioinformatics

Gene Symbol CACNA1E