BOP1 Antibody Summary
Immunogen |
The immunogen recognized by this antibody maps to a region between residue 300 and 350 of human block of proliferation 1 using the numbering given in entry NP_056016.1 (GeneID 23246). |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
BOP1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunoprecipitation 2-5 ug/mg lysate
- Western Blot 1:2000-1:10000
|
Theoretical MW |
84 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
TBS and 0.1% BSA |
Preservative |
0.09% Sodium Azide |
Concentration |
0.2 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for BOP1 Antibody
Background
BOP1 (block of proliferation 1) is a component of the PeBoW (Pes1, Bop, WDR12) complex that plays a role in the processing of 28S and 5.8S ribosomal RNAs and the formation of the 60S ribosome. BOP1 contains seven WD repeats and was originally identified as a cDNA which inhibited cell proliferation. The deregulation of the BOP1 gene is proposed to contribute to colorectal tumorigenesis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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