beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody [DyLight 550] Summary
Immunogen |
A synthetic peptide made to a C-terminal portion of the human B3GAT1 protein (between residues 250-300) [UniProt Q9P2W7] |
Localization |
Golgi apparatus membrane; Single-pass type II membrane protein. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
B3GAT1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Paraffin
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Immunogen affinity purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody [DyLight 550]
Background
CD57 (also known as beta-1,3-glucuronyltransferase 1, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Glucuronosyltransferase P, Human Natural Killer 1, B3GAT1, NK1, HNK1, LEU7, NK-1, GLCUATP, and GLCATP) is a member of the glucuronyltransferase gene family. The enzymes produced by the members of this family recognize non-reducing terminal sugars and their anomeric linkages by exhibiting strong acceptor specificity. CD57 is also involved in the biosynthesis of glycosaminoglycan and L2/HNK-1 carbohydrate epitopes on glycoproteins. CD57 is expressed mainly in the brain and several alternate transcriptional splice variants have been characterized. In cancer research, CD57 positive lymphocytes have been used successfully in monitoring the progression of various cancers (PMID: 21491089). HNK1 is also involved in synaptic plasticity and neurodevelopment (PMID: 20950796).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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Isotype Controls
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