Attractin Antibody - BSA Free

Attractin is a serum glycoprotein of 175 kDaand found in both membrane-bound and secreted forms as a result of alternative splicing. Both the secreted and membrane-bound forms of attractin may be involved in the development and maintenance of the central nervous system. Membrane-bound attractin is a co-receptor for Agouti, antagonist of melanocortin-1 receptor. Secreted attractin, expressed by activated T lymphocytes and modulates interactions between T cells and monocytes/macrophages, was examined as a potential marker of immune activity. Attractinmay be a component of a pathway for regulated protein turnover that also involves mahogunin, a wide-expressed E3 ubiquitinligase found at particularly high levels in the brain. Attractinwas considered as an extracellular target amenable for the development of obesity-regulating drugs, also.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IHC-P, WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-87967	Applications	Species
Winge SB, Nielsen J, Jorgensen A et al. Biglycan is a novel binding partner of fibroblast growth factor receptor 3c (FGFR3c) in the human testis. Mol. Cell. Endocrinol. 2014-09-23 [PMID: 25260943] (IHC-P, WB, Human) Details: Attractin/ATRN antibody used for IHC-P on human testes at 1:200 dilution of primary with 10 mM citrate pH 6 antigen retrieval method - Fig.?2 shows the ATRN expression primarily in the spermatocytes and spermatids. Antibody also used for WB at 1:400 dilution - Figure S2 shows the WB image of ATTN in Human Testes and Prostate lysates - 230?kDa band corresponding to the glycosylated form, 160?kDa band corresponding to the non-glycosylated form and 130?kDa/55?kDa corresponding to truncated forms.	IHC-P, WB	Human
Wu CC, Hsu CW, Chen CD et al. Candidate Serological Biomarkers for Cancer Identified from the Secretomes of 23 Cancer Cell Lines and the Human Protein Atlas. Mol Cell Proteomics 2010-06-01 [PMID: 20124221]

Array NBP1-87967

• Attractin Antibodies
• Attractin ELISA Kits
• Attractin Protein
• Attractin Proteins and Enzyme