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ATP7b Antibody [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IP, WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-360AF350
Alexa Fluor 405
NB100-360AF405
Alexa Fluor 488
NB100-360AF488
Alexa Fluor 532
NB100-360AF532
Alexa Fluor 594
NB100-360AF594
Alexa Fluor 647
NB100-360AF647
Alexa Fluor 700
NB100-360AF700
Alexa Fluor 750
NB100-360AF750
Allophycocyanin
NB100-360APC
Biotin
NB100-360B
CoraFluor 1
NB100-360CL1
DyLight 350
NB100-360UV
DyLight 405
NB100-360V
DyLight 550
NB100-360R
DyLight 594
NB100-360DL594
DyLight 650
NB100-360C
DyLight 680
NB100-360FR
DyLight 755
NB100-360IR
FITC
NB100-360F
HRP
NB100-360H
Janelia Fluor 525
NB100-360JF525
Janelia Fluor 549
NB100-360JF549
Janelia Fluor 585
NB100-360JF585
Janelia Fluor 635
NB100-360JF635
Janelia Fluor 646
NB100-360JF646
Janelia Fluor 669
NB100-360JF669
PE
NB100-360PE
PerCP
NB100-360PCP
Unconjugated
NB100-360
mFluor Violet 450 SE
NB100-360MFV450
mFluor Violet 500 SE
NB100-360MFV500
mFluor Violet 610 SE
NB100-360MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-360
BSA Free
NB100-360
BSA Free
NB100-360SS
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ATP7b Antibody [DyLight 488] Summary

Immunogen
A synthetic peptide made to an internal sequence near the N-terminus of human ATP7b. [UniProt# P35670]
Localization
Golgi apparatus; Predominantly found in trans-Golgi network membrane; multi-pass membrane protein (By similarity). Isoform 2: Cytoplasm. The cleaved form WND/140 kDa is located in mitochondria.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATP7B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoblotting
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ATP7b Antibody [DyLight 488]

  • ATPase, Cu(2+)- transporting, beta polypeptide
  • ATPase, Cu++ transporting, beta polypeptide
  • Copper pump 2
  • copper-transporting ATPase 2
  • EC 3.6.3
  • EC 3.6.3.4
  • PWD
  • WC1
  • WD
  • Wilson disease-associated protein
  • WNDATPase, Cu++ transporting, beta polypeptide (Wilson disease)

Background

ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ATP7B