ATP7b Products

Description

ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; form A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.

Bioinformatics

Entrez	11979 Mouse 540 Human
Uniprot	NP_000044 Human P35670 Human
Product By Gene ID	540
Alternate Names	ATPase, Cu(2+)- transporting, beta polypeptide ATPase, Cu++ transporting, beta polypeptide Copper pump 2 copper-transporting ATPase 2 EC 3.6.3 EC 3.6.3.4 PWD WC1 WD Wilson disease-associated protein WNDATPase, Cu++ transporting, beta polypeptide (Wilson disease)

Research Areas for ATP7b

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