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ALK-7/Activin Receptor Type 1C Antibody (118311) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
118311
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

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ALK-7/Activin Receptor Type 1C Antibody (118311) [Janelia Fluor® 669] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant rat ALK‑7
Leu26-Arg108
Accession # NP_620790
Specificity
Detects rat ALK-7 in Western blots. In Western blots, no cross-reactivity with recombinant human Activin R1B is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
ACVR1C
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ALK-7/Activin Receptor Type 1C Antibody (118311) [Janelia Fluor® 669]

  • activin A receptor, type IC
  • Activin receptor type IC
  • activin receptor type-1C
  • Activin receptor-like kinase 7
  • Activin RIC
  • ACTR-IC
  • ACVR1C
  • ACVRLK7
  • ALK7
  • ALK-7
  • ALK7ALK-7
  • EC 2.7.11
  • EC 2.7.11.30

Background

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type Ireceptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interactdirectly with DNA or in complex with other transcription factors (Bondestam et al., 2001 (PubMed 12063393)).(suppliedby OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ACVR1C