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ALDH18A1 Antibody

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Immunoprecipitation:ALDH18A1 AntibodyNBP3-30292] -Detection of human ALDH18A1/P5CS by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ALDH18A1/P5CS antibody NBP3-30292 (lot NBP3-30292-1) used for IP at 6 µg per reaction. ALDH18A1/P5CS was also immunoprecipitated by rabbit anti-ALDH18A1/P5CS.. For blotting immunoprecipitated ALDH18A1/P5CS, NBP3-30292 was used at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Immunoprecipitation:ALDH18A1 AntibodyNBP3-30292] -Detection of human ALDH18A1/P5CS by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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ALDH18A1 Antibody Summary

Immunogen
Between 745 and 795
Assay Type
[Assay Type]
Sample Volume
[Sample Volume]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ALDH18A1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-citrate/phosphate pH 7 -8.
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for ALDH18A1 Antibody

  • aldehyde dehydrogenase 18 family, member A1
  • Aldehyde dehydrogenase family 18 member A1
  • delta-1-pyrroline-5-carboxylate synthase
  • EC 2.1.2.11
  • EC 2.3.3.13
  • GSASdelta1-pyrroline-5-carboxlate synthetase
  • MGC117316
  • P5CSdelta-1-pyrroline-5-carboxylate synthetase
  • PYCSEC 1.2.1.41
  • pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)

Background

ALDH18A1, or Delta-1-pyrroline-5-carboxylate synthase, contains a long 88 kDa and a short 87 kDa isoform, and is involved in the catalytic conversion of glutamate to glutamate 5-semialdehyde. Current research on ALDH18A1 is being conducted to determine the relation between the protein and a variety of diseases and disorders, including neurodegeneration, pneumonia, connective tissue disease, mental retardation, hypoornithinemia, tuberculosis, microcephaly, Alzheimer's disease, gastroesophageal reflux disease, and dementia. The protein has been linked to biosynthesis and metabolic pathways where it interacts with PUS1, UQCRFS1, ICT1, OAT, and MYC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ALDH18A1 Antibody
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ALDH18A1 Antibody
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Bioinformatics

Gene Symbol ALDH18A1