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AF4 Antibody [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IP (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

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AF4 Antibody [DyLight 488] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human proto-oncogene AF4 using the numbering given in entry NP_005926.1 (GeneID 4299).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AFF1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for AF4 Antibody [DyLight 488]

  • AF-4
  • AF4/FMR2 family member 1
  • AF4/FMR2 family, member 1
  • AF4myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 2
  • ALL1-fused gene from chromosome 4 protein
  • FEL
  • MLLT2MGC134969
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 2
  • PBM1
  • pre-B-cell monocytic leukemia partner 1
  • Protein AF-4
  • Protein FEL
  • Proto-oncogene AF4

Background

AF4 is a member of the AF4/LAF4/FMR2 (ALF) family of transcription cofactors. It has been identified as part of a translocation [t(4:11)(q21;q23)] found in patients with acute leukemia involving MLL/HRX. AF4 functions as a cofactor of transcriptional elongation and chromatin remodeling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol AFF1