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Adenylate Cyclase 3 Antibody

Images

 
Western Blot: Adenylate Cyclase 3 Antibody [NBP2-60792] - Western blot of rat cortical lysate showing specificimmunolabeling of the ~160 kDa adenylate cyclase III protein.
Immunocytochemistry/ Immunofluorescence: Adenylate Cyclase 3 Antibody [NBP2-60792] - Immunofluorescence of a section of rat hippocampus selectively labeling the neuronal cilia with anti-adenylate cyclase III (1:10,000, ...read more
Immunocytochemistry/ Immunofluorescence: Adenylate Cyclase 3 Antibody [NBP2-60792] - Immunofluorescence of cultured rat neurons and glia showingstrong staining of neuronal cilia using our anti-adenylatecyclase III ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Adenylate Cyclase 3 Antibody Summary

Immunogen
Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # P21932
Specificity
Specific for endogenous levels of the ~160 kDa adenylate cyclase 3 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADCY3
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Western Blot 1:100-1:2000
Application Notes
WB analysis shows bands at 160, 200 kDa
Theoretical MW
160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS with 50% glycerol
Preservative
0.035% Sodium Azide
Purity
Antigen Affinity-purified

Alternate Names for Adenylate Cyclase 3 Antibody

  • AC3
  • AC3EC 4.6.1.1
  • AC-III
  • ADCY3
  • Adenylate Cyclase 3
  • adenylate cyclase type 3
  • Adenylate cyclase type III
  • Adenylyl cyclase 3
  • adenylyl cyclase, type III
  • ATP pyrophosphate-lyase 3
  • EC 4.6.1
  • KIAA0511
  • olfactive type

Background

ADCY3, also known as Adenylate cyclase type 3, is a 129 kDa 1,144 amino acid protein, and is involved in the formation of the secondary messenger protein, cAMP. This protein has also been shown to have interactions with STOML3, CAMK2G, PDE1A, PDE1C, and PDE2A in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY3 and cholera, alcoholism, tuberculosis, and breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Adenylate Cyclase 3 Antibody (NBP2-60792) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADCY3