Adenosine A2b R Antibody (2683F) [Unconjugated] Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Human Adenosine A2b R synthetic peptide Accession # NP_000667 |
Specificity |
Detects human Adenosine A2b R in direct ELISAs. |
Source |
N/A |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Purity Statement |
Protein A or G purified from cell culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 0.25 ug/10^6 cells
|
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Reconstitution Instructions |
Reconstitute at 0.5 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Adenosine A2b R Antibody (2683F) [Unconjugated]
Background
ADORA2B (Adenosine B2a Receptor, Adora-B2) is a widely
expressed seven transmembrane G protein-coupled receptor (GPCR) activated by
adenosine. Studies show that adenosine is crucial for ischemic preconditioning
(IP) via its receptors ADORA1, ADORA2a and ADORA2b. All of these receptors are
expressed in the myocardium and have been implicated in the role of
cardioprotection during ischemia. Human and mouse Adora2B sequences are 88%
identical over the full protein, but only 77% identical on the extra-cellular domains,
including N-term tail and three loops.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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