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Adenosine A2b R Antibody (1022311) [Unconjugated]

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Western blot shows lysates of A431 human epithelial carcinoma cell line and human cerebeullum tissue. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Adenosine A2b R Monoclonal Antibody (Catalog # MAB10444) ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
1022311
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Catalog# & Formulation Size Price
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Adenosine A2b R Antibody (1022311) [Unconjugated] Summary

Immunogen
Synthetic peptide containing human Adenosine A2b R
Specificity
Detects human Adenosine A2b R in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Adenosine A2b R Antibody (1022311) [Unconjugated]

  • Adenosine A2b R
  • adenosine A2b receptor
  • Adenosine A2bR
  • adenosine receptor A2b
  • ADORA2
  • ADORA2B

Background

ADORA2B (Adenosine B2a Receptor, Adora-B2) is a widely expressed seven transmembrane G protein-coupled receptor (GPCR) activated by adenosine. Studies show that adenosine is crucial for ischemic preconditioning (IP) via its receptors ADORA1, ADORA2a and ADORA2b. All of these receptors are expressed in the myocardium and have been implicated in the role of cardioprotection during ischemia. Human and mouse Adora2B sequences are 88% identical over the full protein, but only 77% identical on the extra-cellular domains, including N-term tail and three loops.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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