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ABCA7 Antibody [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-82069AF350
Alexa Fluor 405
NBP2-82069AF405
Alexa Fluor 488
NBP2-82069AF488
Alexa Fluor 532
NBP2-82069AF532
Alexa Fluor 594
NBP2-82069AF594
Alexa Fluor 647
NBP2-82069AF647
Alexa Fluor 700
NBP2-82069AF700
Alexa Fluor 750
NBP2-82069AF750
Biotin
NBP2-82069B
CoraFluor 1
NBP2-82069CL1
DyLight 405
NBP2-82069V
DyLight 488
NBP2-82069G
DyLight 550
NBP2-82069R
DyLight 594
NBP2-82069DL594
DyLight 650
NBP2-82069C
DyLight 680
NBP2-82069FR
DyLight 755
NBP2-82069IR
FITC
NBP2-82069F
HRP
NBP2-82069H
Janelia Fluor 525
NBP2-82069JF525
Janelia Fluor 549
NBP2-82069JF549
Janelia Fluor 585
NBP2-82069JF585
Janelia Fluor 635
NBP2-82069JF635
Janelia Fluor 646
NBP2-82069JF646
Janelia Fluor 669
NBP2-82069JF669
PerCP
NBP2-82069PCP
Unconjugated
NBP2-82069
mFluor Violet 450 SE
NBP2-82069MFV450
mFluor Violet 500 SE
NBP2-82069MFV500
mFluor Violet 610 SE
NBP2-82069MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-82069
BSA Free
NBP2-82069
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ABCA7 Antibody [DyLight 350] Summary

Immunogen
ABCA7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ABCA7. The immunogen is located within amino acids 130 - 180 of ABCA7. Amino Acid Squence: AQPQPTKQSPLEPPMLDV
Specificity
ABCA7 antibody is predicted to not cross-react with other ABC1 subfamily proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABCA7
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ABCA7 Antibody [DyLight 350]

  • ABCA-SSN
  • ABCXATP-binding cassette sub-family A member 7
  • ATP-binding cassette, sub-family A (ABC1), member 7
  • Autoantigen SS-N
  • EC 2.2.1.1
  • EC 3.6.3
  • EC 3.6.3.41
  • FLJ40025
  • Macrophage ABC transporter

Background

ATP-binding cassette sub-family A member 7 (ABCA7), is a member of the ATP-binding cassette sub-family A. ABCA7 is thought to have a role in phagocytosis apoptotic cells macrophages.

ABCA-7 is highly homologous to ABCA1, and also mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. It also may mediate cholesterol efflux.

ABCA7 antibodies are useful for studies of cholesterol formation and lipid processing mechanisms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ABCA7