A2BP1 Antibody (D8H8)

A2BP1, also known as Ataxin-2-binding protein 1, Fox-1 homolog A and Rbfox1, is a member of the Fox-1 family, which is made up of RNA-binding proteins. A2BP1 regulates tissue-specific alternative splicing during erythropoiesis by locating the UGCAUG sequence and binding to the 5'-splice site while also preventing U2AF2 from binding to the 3' splicing site. A2BP1 may play a role in restricting the pathology of spinocerebellar ataxia type 2 (SCA2). The SCA2 gene produces ataxin-2 proteins which is a cause of familial neurodegenerative diseases. A2BP1 is primarily found in the nucleus but also seen in the cytoplasm and is expressed in the brain, heart, neurons, skeletal muscle, and embryo.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: IF/IHC, IHC-Fr, PCR.

Showing Publications 1 - 4 of 4.

Publications using NBP2-13169	Applications	Species
Gu L, Caprioli J, Piri N Rbfox1 expression in amacrine cells is restricted to GABAergic and VGlut3 glycinergic cells Bioscience reports 2022-06-22 [PMID: 35730583] (IF/IHC, Mouse)	IF/IHC	Mouse
Gu L, Kawaguchi R, Caprioli J, Piri N The effect of Rbfox2 modulation on retinal transcriptome and visual function J Mol Med (Berl) 2020-11-06 [PMID: 33184471]
Lund C, Yellapragada V, Vuoristo S et al. Characterization of the human GnRH neuron developmental transcriptome using a GNRH1-TdTomato reporter line in human pluripotent stem cells Dis Model Mech 2020-01-29 [PMID: 31996360] (PCR, Human)	PCR	Human
Gu L, Bok D, Yu F et al. Downregulation of splicing regulator RBFOX1 compromises visual depth perception. PLoS ONE. 2018-07-12 [PMID: 30001398] (IHC-Fr, Mouse)	IHC-Fr	Mouse

Array NBP2-13169

• A2BP1 Antibodies
• A2BP1 Lysates
• A2BP1 Proteins