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5-Lipoxygenase Antibody [Janelia Fluor® 646]

 
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Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, RbSpecies Glossary
Applications WB, Simple Western
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-58749AF350
Alexa Fluor 405
NB110-58749AF405
Alexa Fluor 488
NB110-58749AF488
Alexa Fluor 532
NB110-58749AF532
Alexa Fluor 594
NB110-58749AF594
Alexa Fluor 647
NB110-58749AF647
Alexa Fluor 700
NB110-58749AF700
Alexa Fluor 750
NB110-58749AF750
Allophycocyanin
NB110-58749APC
Biotin
NB110-58749B
CoraFluor 1
NB110-58749CL1
DyLight 350
NB110-58749UV
DyLight 405
NB110-58749V
DyLight 488
NB110-58749G
DyLight 550
NB110-58749R
DyLight 594
NB110-58749DL594
DyLight 650
NB110-58749C
DyLight 680
NB110-58749FR
DyLight 755
NB110-58749IR
HRP
NB110-58749H
Janelia Fluor 525
NB110-58749JF525
Janelia Fluor 549
NB110-58749JF549
Janelia Fluor 585
NB110-58749JF585
Janelia Fluor 635
NB110-58749JF635
Janelia Fluor 669
NB110-58749JF669
PE
NB110-58749PE
PerCP
NB110-58749PCP
Unconjugated
NB110-58749
mFluor Violet 450 SE
NB110-58749MFV450
mFluor Violet 500 SE
NB110-58749MFV500
mFluor Violet 610 SE
NB110-58749MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-58749
BSA Free
NB110-58749
BSA Free
NB110-58749SS
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5-Lipoxygenase Antibody [Janelia Fluor® 646] Summary

Immunogen
A synthetic peptide made to a C-terminal region within residues 600-674 of human 5-Lipoxygenase. [Swiss-Prot# P09917]
Localization
Cytoplasmic
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ALOX5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for 5-Lipoxygenase Antibody [Janelia Fluor® 646]

  • 5Lipoxygenase
  • 5-Lipoxygenase
  • 5-LO
  • 5-LOX
  • 5LPG
  • ALOX5
  • arachidonate 5-lipoxygenase
  • arachidonic 5-lipoxygenase alpha-10 isoform
  • arachidonic 5-lipoxygenase delta-10-13 isoform
  • arachidonic 5-lipoxygenase delta-13 isoform
  • arachidonic 5-lipoxygenase delta-p10 isoform
  • arachidonic acid 5-lipoxygenase
  • EC 1.13.11
  • EC 1.13.11.34
  • leukotriene A4 synthase
  • LOG5
  • LOX5A
  • MGC163204

Background

5 Lipoxygenase encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB110-58749JF646
5-Lipoxygenase Antibody [Janelia Fluor® 646]
Species: Hu, Mu, Rt, Bv, Rb
Applications: WB, Simple Western

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Bioinformatics

Gene Symbol ALOX5