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5-Lipoxygenase Antibody (OTI3F1) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI3F1
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70166AF350
Alexa Fluor 405
NBP2-70166AF405
Alexa Fluor 488
NBP2-70166AF488
Alexa Fluor 532
NBP2-70166AF532
Alexa Fluor 594
NBP2-70166AF594
Alexa Fluor 647
NBP2-70166AF647
Alexa Fluor 700
NBP2-70166AF700
Alexa Fluor 750
NBP2-70166AF750
Allophycocyanin
NBP2-70166APC
Biotin
NBP2-70166B
CoraFluor 1
NBP2-70166CL1
DyLight 350
NBP2-70166UV
DyLight 405
NBP2-70166V
DyLight 488
NBP2-70166G
DyLight 550
NBP2-70166R
DyLight 594
NBP2-70166DL594
DyLight 650
NBP2-70166C
DyLight 680
NBP2-70166FR
DyLight 755
NBP2-70166IR
FITC
NBP2-70166F
HRP
NBP2-70166H
Janelia Fluor 525
NBP2-70166JF525
Janelia Fluor 549
NBP2-70166JF549
Janelia Fluor 585
NBP2-70166JF585
Janelia Fluor 635
NBP2-70166JF635
Janelia Fluor 646
NBP2-70166JF646
PE
NBP2-70166PE
PerCP
NBP2-70166PCP
Unconjugated
NBP2-46513
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-46513
Azide and BSA Free
NBP2-70166
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5-Lipoxygenase Antibody (OTI3F1) [Janelia Fluor® 669] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 18-364 of human ALOX5(NP_000689) produced in E.coli.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
ALOX5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for 5-Lipoxygenase Antibody (OTI3F1) [Janelia Fluor® 669]

  • 5Lipoxygenase
  • 5-Lipoxygenase
  • 5-LO
  • 5-LOX
  • 5LPG
  • ALOX5
  • arachidonate 5-lipoxygenase
  • arachidonic 5-lipoxygenase alpha-10 isoform
  • arachidonic 5-lipoxygenase delta-10-13 isoform
  • arachidonic 5-lipoxygenase delta-13 isoform
  • arachidonic 5-lipoxygenase delta-p10 isoform
  • arachidonic acid 5-lipoxygenase
  • EC 1.13.11
  • EC 1.13.11.34
  • leukotriene A4 synthase
  • LOG5
  • LOX5A
  • MGC163204

Background

5 Lipoxygenase encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-70166JF669
5-Lipoxygenase Antibody (OTI3F1) [Janelia Fluor® 669]
Species: Hu, Mu, Rt
Applications: WB, IHC

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Bioinformatics

Gene Symbol ALOX5