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5-HT3E Antibody

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Immunohistochemistry-Paraffin: 5-HT3E Antibody [NBP2-33578] - Staining of human duodenum shows strong cytoplasmic positivity in a subset of glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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5-HT3E Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: LAFILSRATPRPALGPLSYREHRVALLHLTHSMSTTGRGVTFTINCSGF
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HTR3E
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
5-HT3E Protein (NBP2-33578PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for 5-HT3E Antibody

  • 5-HT3 receptor subunit E splice variant HTR3Ea
  • 5-HT3c1
  • 5-HT3c1,5-HT3E
  • 5HT3E
  • 5-HT3E
  • 5-hydroxytryptamine (serotonin) receptor 3, family member E
  • 5-hydroxytryptamine receptor 3E
  • HTR3E
  • MGC120035
  • MGC120036
  • serotonin receptor 3E

Background

The product of the HTR3E gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E ofthe type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, ahormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encodingsubunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its fulllength sequence has not been determined. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HTR3E
Uniprot